Palabras clave: alcoholismo, enfermedad de Marchiafava-Bignami, atrofia del cuerpo calloso, demencia Abstract Chronic alcoholism causes toxicity in the central and peripheral nervous system, Marchiafava-Bignami disease being one of its less frequent complications. This entity is characterized by demyelinization of the callous body. The clinical picture is varied, the most frequent symptoms being: dementia, attention disorders, gait difficulty and interhemispheric deconnection syndrome. Neuroimaging techniques, basically magnetic resonance imaging, are required for its diagnosis. We present the case of a patient who was admitted to the intensive care unit due to neurological deterioration and respiratory arrest.

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CiteScore measures average citations received per document published. The Journal accepts works on basic as well applied research on any field of neurology. Marchiafava—Bignami disease — Wikipedia It classically involves the central layers with relative sparing of the dorsal and ventral extremes which may be seen as a sandwich sign on sagittal MRI imaging.

Si continua navegando, consideramos que acepta su uso. You can change marchisfava settings or obtain more information by clicking here. Marchiafava-Bignami disease MBD in a non alcoholic patient: You can change the settings or obtain more information by clicking here. She was admitted due to a 1-month history of memory loss, confusion, delirium, and gait disorder.

Marchiafsva Monday to Friday from 9 a. Focal Generalised Status epilepticus Myoclonic epilepsy. Case 4 Case 4. Support Radiopaedia and see fewer ads. Infobox medical condition new. Continuing navigation will be considered as acceptance of this use.

Check for errors and try again. Log in Sign up. We present a case of MBD in which poorly-controlled diabetes mellitus is suggested as the aetiopathogenic mechanism. It is thought to be linked to B 12 and folate deficiencies in malnourished patients. Subscribe to our Newsletter. On the microscopic level, loss of oligodendrocytes with abundant macrophages can be observed.

Rev Neurol, 35pp. Brain Encephalitis Viral encephalitis Herpesviral encephalitis Limbic encephalitis Encephalitis lethargica Cavernous sinus thrombosis Brain abscess Amoebic. Before the use of such imaging equipment, it was unable to be diagnosed until autopsy.

You enfegmedad change the settings or obtain more information by clicking here. Loading Stack — 0 images remaining. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. This item has received. Marchiafava—Bignami disease Rev Neurol, 28pp. Marchiafava—Bignami disease is a progressive neurological disease of alcoholism, characterized by corpus callosum demyelination and necrosis and subsequent atrophy.

Individuals with MBD usually have a history of alcohol abuse, but this is not always the case. J Neurol,pp. MBD is an msrchiafava disorder first described in by 2 Italian pathologists who performed autopsies on 3 alcoholic patients with rapidly progressing symptoms of neurological impairment.

Administration of vitamin B complex results in improvement in many patients, although some do not recover and may die of the disease 2. Some treatments work extremely well with some patients and not at all with others. Unable to process the form. We marfhiafava that, in addition to classic risk factors, osmotic changes associated with glycaemic fluctuations, and possibly changes in other electrolytes or particles which alter normal blood osmotic concentration, can cause this disease.

Others remain in comas that eventually lead to death. J Clin Neurosci, 19pp. The examination revealed bradypsychia and disorientation in time, space, and person; as a sign of interhemispheric disconnection, she marchkafava left-sided ideomotor apraxia when attempting to follow directions. Synonyms or Alternate Spellings: Marchiafava—Bignami disease is routinely diagnosed with the use of an MRI because the majority of clinical symptoms are non-specific.

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